Month: August 2021

Postmortem genetic testing, or genomic autopsy, of young individuals who experienced sudden death revealed many had known genetic variants that are associated with cardiomyopathy, according to a Northwestern Medicine study published in JAMA Cardiology. These findings indicate that genomic autopsy can improve care for families after a sudden death in a young patient, as it
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Receiving treatment with a biologic medication, compared with no biologic treatment, appeared to be associated with a lower risk for developing psoriatic arthritis (PsA) in patients with psoriasis. That’s according to the results of a nested case-control study involving electronic medical record data from an Israeli health maintenance organization in Arthritis & Rheumatology. Compared with no
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What is it that makes a simple jigsaw puzzle such an effective mindfulness practice? It’s the rainy day classic that became a lockdown essential, and while there’s nothing new about puzzles (the first jigsaw is thought to have been created in 1762), many of us are just starting to realise the potentially mindful boost that
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Treatment for Prevention of COVID-19 Pfizer and BioNTech Initiate Rolling Submission of Supplemental Biologics License Application to U.S. FDA for Booster Dose of Comirnaty in Individuals 16 and Older New Phase 3 data show booster (third) dose of Comirnaty induces significant SARS-CoV-2 neutralizing antibody titers and demonstrated a favorable safety and tolerability profile SARS-CoV-2 neutralizing
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ATLANTA, Aug. 30, 2021 /PRNewswire/ — UCB announced today that the U.S. Food and Drug Administration (FDA) has approved an expanded indication for Briviact (brivaracetam) CV tablets, oral solution, and injection to treat partial-onset seizures in patients as young as one month of age.2 This is the first time that the IV formulation of Briviact
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Taiwan is banking on a homegrown Covid-19 shot to speed up its inoculation program as the island and many countries struggle to secure vaccine deliveries from major drug companies. The locally produced Covid vaccine from Medigen Vaccine Biologics was rolled out last week, with President Tsai Ing-wen receiving her first shot of the two-dose vaccine
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Since the COVID-19 pandemic reached the United States in early 2020, scientists have struggled to find laboratory models of SARS-CoV-2 infection, the respiratory virus that causes COVID-19. Animal models fell short; attempts to grow adult human lungs have historically failed because not all of the cell types survived. Undaunted, stem cell scientists, cell biologists, infectious
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Public health authorities have been persuading the general masses to get the COVID-19 booster shots once they have become available. But the guidance has mostly been for those who received the mRNA vaccines from Pfizer and Moderna, leaving recipients of Johnson & Johnson’s Janssen vaccine wondering if they also need the additional dose of the vaccine. 
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ABBOTT PARK, Ill., Aug. 27, 2021.  Abbott today announced results of the landmark GUIDE-HF clinical trial, a 1,000 patient randomized study designed to assess the benefits of the CardioMEMS HF System in people living with NYHA Class II, III and IV heart failure. Data adjusted for the impact of COVID-19 show a strong reduction in
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A new noninvasive procedure is safe and effective for treating patients with mild Alzheimer’s disease (AD), new research suggests. The approach uses MRI-guided low-intensity focused ultrasound (FUS) and injected microbubbles to temporarily open the blood-brain barrier (BBB). In a small group of patients, the procedure was significantly associated with reduced amyloid plaque and cognitive decline.
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Pulp is the soft mass of connective tissue that is located in the center of the tooth. Dental pulp also contains nerves and blood vessels to provide essential nutrients to keep the tooth healthy and working properly. A pulpectomy is the removal of pulp tissue from all parts of a tooth that has become irreversibly
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elamipretide Treatment for Barth Syndrome Stealth BioTherapeutics Submits Elamipretide New Drug Application to FDA for Treatment of Barth Syndrome BOSTON, Aug. 24, 2021 /PRNewswire/ – Stealth BioTherapeutics Corp (Nasdaq: MITO), a clinical-stage biotechnology company focused on the discovery, development, and commercialization of novel therapies for diseases involving mitochondrial dysfunction, today announced the submission of a New Drug Application (NDA)
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PRINCETON, N.J.–(BUSINESS WIRE) August 20, 2021 — Bristol Myers Squibb (NYSE: BMY) today announced that Opdivo (nivolumab) 240 mg every two weeks or 480 mg every four weeks (injection for intravenous use) was approved by the U.S. Food and Drug Administration (FDA) for the adjuvant treatment of patients with urothelial carcinoma (UC) who are at
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An Israeli man receives a third shot of coronavirus disease (COVID-19) vaccine as country launches booster shots for over 30-year-olds, in Rishon Lezion, Israel August 24, 2021. Nir Elias | Reuters Israeli lawmakers are keen to avoid another lockdown after overseeing one of the world’s fastest vaccination drives. New daily coronavirus infections, however, have just
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A deep look into a nationwide mass vaccination setting in Israel revealed that the BNT162b2 (Pfizer–BioNTech) vaccine is not linked with an elevated risk of a majority of the adverse events under study, with the exception of myocarditis. However, even that potentially severe adverse event is much more pervasive following the infection with severe acute
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Finerenone (Kerendia) prevents cardiovascular (CV) and some renal events in type 2 diabetes patients with earlier stages of kidney disease, the FIGARO-DKD trial showed. In the trial’s stage 1 to 4 kidney disease patients with moderate-to-severe albuminuria, the nonsteroidal mineralocorticoid receptor antagonist (MRA) reduced the composite of CV death, nonfatal myocardial infarction or stroke, or
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In patients with coronary artery disease scheduled for a percutaneous intervention (PCI), fractional flow reserve (FFR) assessment at the time of angiography significantly improves outcome, but it has no apparent value as a routine study in all CAD patients, according to the randomized RIPCORD 2 trial. When compared to angiography alone in an all comer-strategy,
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Until now, patients with heart failure with preserved ejection fraction – the most common type of heart failure in the elderly – have had no access to evidenced-based treatments. For the first time, a large clinical trial led by Prof. Dr. Stefan Anker from Charité – Universitätsmedizin Berlin has identified a drug which has a
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The addition of image-guided atrial fibrosis ablation did not significantly reduce the risk of recurrence relative to pulmonary vein isolation (PVI) alone in patients with treatment-resistant atrial fibrillation (AFib), according to results of an intention-to-treat analysis of the randomized DECAAF II trial. However, there was a significant advantage for the addition of image-guided ablation in
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Family bonds often run the deepest, which is why it’s all the more painful when they break down. Here, with the help of a counsellor, we explore how to navigate difficult family relationships Families: they’re not always easy. Separation, blended households, addictions, mental illness, money problems, betrayal, expectations, communication, or simply clashing personalities – there
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There’s nothing quite like it. The feeling of nausea you get after you eat something that doesn’t agree with you. Now imagine dealing with that sickly feeling 24/7. Unfortunately, that’s reality for diabetics who have what’s called gastroparesis. Their stomachs don’t empty normally and treatments often don’t work. But thanks to doctors at Mayo Clinic,
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Elizabeth Holmes, founder and former CEO of Theranos, arrives for motion hearing on Monday, Nov. 4, 2019, at the U.S. District Court House inside Robert F. Peckham Federal Building in San Jose, California. Yichuan Cao | NurPhoto | Getty Images In a bombshell revelation just days before her criminal fraud trial, defense attorneys for Elizabeth
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Researchers with the Vanderbilt Diabetes Research and Training Center (DRTC) at Vanderbilt University Medical Center led a multisite study which has demonstrated that, when controlled and standardized, quantitative magnetic resonance imaging (MRI) of the pancreas is highly reproducible when using different MRI hardware and software at different geographic locations. This finding opens up a new
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