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Adjuvant pembrolizumab (Keytruda) following complete melanoma resection could soon move to an earlier stage in the management of high-risk disease, suggest results from KEYNOTE 716. However, the results raise many questions, says an expert invited to discuss the new data. Adjuvant pembrolizumab is already approved in the USA for use in patients with melanoma with
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The visual disorder amblyopia, also known as “lazy eye,” can be impossible to treat once children reach adolescence. Now, a new Israel study links cases in older teenagers to higher rates of poverty, below-average cognitive scores, immigrant status, and obesity.   The research suggests that poorer children need more visual screening, especially in the United States
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Details of what works, and what doesn’t, in triple-negative breast cancer (TNBC) come from long-term follow-up of the phase 3 randomized BrighTNess trial. The initial improvement that was seen in pathologic complete response (pCR) rates with the addition of carboplatin to paclitaxel and standard neoadjuvant chemotherapy translated into improved event-free survival (EFS) rates in patients
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On September 1, Texas Senate Bill 8 went into effect. While the law’s stated goal is to severely limit a woman’s constitutional right to an abortion in Texas, it also designates private citizens to sue not just abortion providers, but anyone “aiding and abetting” a woman seeking to obtain an abortion after 6 weeks of
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New evidence suggesting that the benefit of ticagrelor outweighs the risk when added to aspirin for 30 days after a mild-to-moderate ischemic stroke or high-risk transient ischemic attack (TIA) has been reported from a secondary analysis of the THALES trial. The new analysis was presented at the recent European Stroke Organisation Conference (ESOC) and published
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Latest figures have shown that obesity cases are on the rise amid the COVID-19 pandemic. Did the global health crisis play a role in the surge in obesity cases in sixteen states?  The Latest Figures The Centers for Disease Control and Prevention (CDC) reported Wednesday that there has been an increase in the number of
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A single-arm, phase 2 clinical trial of atezolizumab with chemotherapy for patients with nonsquamous non-small cell lung cancer (NSCLC) and brain metastases shows promise for improving progression-free survival, according to a study presented at the 2021 World Congress on Lung Cancer. The trial is noteworthy because to date, few patients with nonsquamous NSCLC and untreated
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Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. The largest nonprofit health system in Texas has secured a temporary restraining order against cardiologist Peter A. McCullough, MD, MPH, a COVID-19 vaccine skeptic who allegedly continued to claim an affiliation with Baylor Scott & White Health months after he entered
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Patients with life-limiting advanced lung cancer often experience intense grief and loss. Addressing patients’ physical symptoms — drug side effects, trouble breathing, pain, fatigue — alongside their psychological and spiritual distress — depression, anxiety, fear of death — is critical to restoring their dignity and improving their quality of life, say palliative care experts. Palliative
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A new study is shedding more light on what could be causing severe COVID-19 infection in SARS-CoV-2 patients.  Stanford researchers revealed this week their interesting discovery upon examining a number of hospitalized COVID-19 patients. In a press release published on Stanford Medicine’s website Tuesday, the team indicated that they found self-attacking antibodies in 1 in
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The FDA approved mobocertinib (Exkivity) as a second-line treatment for locally advanced or metastatic non-small cell lung cancer (NSCLC) harboring EGFR exon 20 insertion mutations, Takeda Pharmaceuticals announced on Wednesday. Approval of the tyrosine kinase inhibitor (TKI) was based on the results of a phase I/II study (EXCLAIM) presented earlier this year at the American
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  Surfing the web today, you may have noticed that the Google Doodle is a nurse, a Latin American one at that. In keeping with the celebration of National Hispanic Heritage Month, the tech giant today honored Panamanian American nurse and educator Ildaura Murillo-Rohde, who helped start the National Association of Hispanic Nurses (NAHN). According
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Note that some links may require registration or subscription. Some people are drinking or gargling povidone iodine (Betadine) to treat COVID-19, causing experts to warn that ingesting the antiseptic is toxic, not helpful in fighting SARS-CoV-2, and may lead to iodine poisoning and kidney failure. (KOKH Oklahoma City; Newsweek) Preventable COVID-19 hospitalizations among unvaccinated adults
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Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. The Chief Executive Officer of a high-volume national nurse staffing firm based in Overland Park, Kansas, has stepped down after questions were raised about his support of an antimask group reportedly started by his 19-year-old son. Brian Cleary had been CEO
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Sleeping well through the night is associated with a lower risk for cardiac arrhythmias, new research suggests. In a large population study with more than 400,000 patients, researchers found a healthy sleep pattern was associated with lower risks for atrial fibrillation (AF) and bradyarrhythmias. A good night’s sleep was associated with a 29% lower risk
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The rise of coronavirus variants has highlighted the huge influence evolutionary biology has on daily life. But how mutations, random chance and natural selection produce variants is a complicated process, and there has been a lot of confusion about how and why new variants emerge. Until recently, the most famous example of rapid evolution was
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Note that some links may require registration or subscription. Booster shots for COVID-19 are not necessary right now, a group of international and U.S. scientists argued after reviewing the existing data; the group includes two FDA vaccine reviewers who recently announced their resignations. (The Lancet) Officials in the Biden administration continue to battle with the
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A new study from Orange County, California, shows how Candida auris, an emerging pathogen, was successfully identified and contained in long-term acute care hospitals (LTACHs) and ventilator-capable skilled-nursing facilities (vSNFs). Lead author Ellora Karmarkar, MD, MSc, formerly an epidemic intelligence service officer with the CDC and currently with the California Department of Public Health, told
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When it comes to keeping yourself hydrated, you can never go wrong with good ol’ water. However, if you’re an active person who’s constantly exercising, your body needs more than just water for recovery and to stay hydrated. Electrolytes are minerals that our bodies use to maintain their natural ionic balance. We can easily load up on electrolytes through sports
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